Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24743781 | 0.84 | USP30 (0.40) | — | |
| SCHEMBL22355670 | 0.83 | OTUD7B (0.32) | — | |
| SCHEMBL24743011 | 0.83 | CYP3A4 (0.41) | — | |
| SCHEMBL22355680 | 0.82 | BACE1 (0.33) | — | |
| SCHEMBL24742987 | 0.80 | MALT1 (0.38) | — | |
| SCHEMBL22355758 | 0.78 | ROCK2 (0.42) | — | |
| Hydrochloric Acid SCHEMBL30328928 | 0.76 | SOS1 (0.39) | KCNJ1KCNH2PIM1 | |
| SCHEMBL24742882 | 0.73 | ITGB3 (0.44) | — | |
| SCHEMBL22396229 | 0.71 | ROCK2 (0.57) | — | |
| SCHEMBL24742821 | 0.70 | MALT1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704121-B1 | DIAZASPIRO ROCK INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2022-12-21 | — | — | EP | disclosed |