Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12221920 | 0.84 | ITGA4 (0.51) | SMN1; SMN2CTSSCTSK | |
| SCHEMBL12198439 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1DPP4SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL28733236 | 0.80 | CTSK (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL10981741 | 0.80 | CTSK (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL10974978 | 0.80 | CTSK (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL948952 | 0.80 | NPC1 (0.49) | ALDH1A1KMT2AMEN1CTSKNPC1 | |
| Hydrochloric Acid SCHEMBL10493771 | 0.78 | NPC1 (0.48) | ALDH1A1KMT2AMEN1CTSKNPC1 | |
| SCHEMBL7561001 | 0.78 | MMP13 (0.39) | ALDH1A1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL2135542 | 0.77 | POLB (0.46) | ALDH1A1KMT2AMEN1OPRK1 | |
| SCHEMBL19456095 | 0.77 | CTSS (0.50) | ALDH1A1KMT2AMEN1HPGDOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |