Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24744882 | 0.88 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL30122007 | 0.88 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL24744883 | 0.75 | MTNR1A (0.34) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL20510109 | 0.73 | FFAR4 (0.52) | ALDH1A1HPGDHSD17B10POLBMEN1 | |
| SCHEMBL31443911 | 0.72 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL18329451 | 0.70 | MAOB (0.43) | ALDH1A1HPGDKDM4EPOLBKMT2A | |
| SCHEMBL24745568 | 0.70 | HPGD (0.39) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL22396845 | 0.70 | NOTUM (0.48) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL22535966 | 0.70 | HPGD (0.47) | ALDH1A1HPGDKDM4EHSD17B10POLB | |
| SCHEMBL12145867 | 0.69 | PKM (0.49) | ALDH1A1HPGDKDM4EHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |