SCHEMBL2474720

SCHEMBL2474720

C=C(C)C(N)=O.C=C(C)C(N)=O.C=C(C)C(N)=O.CCC/C(=C(/C)C(=O)O)[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL514924 0.89 FNTA (0.35)
SCHEMBL4001231 0.89 FNTA (0.35)
SCHEMBL10432248 0.84 ALDH1A1 (0.30)
SCHEMBL8466015 0.81 THRB (0.33)
SCHEMBL9743623 0.74 THRB (0.34)
SCHEMBL290897 0.72 FNTA (0.37)
SCHEMBL886924 0.72 FNTA (0.37)
SCHEMBL3768509 0.71 THRB (0.32)
SCHEMBL5086044 0.71 FNTA (0.36)
SCHEMBL3847687 0.71 FNTA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2374031-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES Novartis AG (CH) 2011-10-12 EP disclosed
WO-2010071691-A1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES NOVARTIS AG (CH) 2010-06-24 WO disclosed