Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514924 | 0.91 | FNTA (0.35) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL4001231 | 0.91 | FNTA (0.35) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL2474720 | 0.81 | TDP1 (0.35) | — | |
| SCHEMBL9743623 | 0.79 | THRB (0.34) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL886924 | 0.77 | FNTA (0.37) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL290897 | 0.77 | FNTA (0.37) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL10432248 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL3768509 | 0.75 | THRB (0.32) | THRBFNTAFNTBPGGT1B | |
| SCHEMBL3847687 | 0.75 | FNTA (0.36) | THRBFNTAFNTBPGGT1BFFAR3 | |
| SCHEMBL5086044 | 0.75 | FNTA (0.36) | THRBFNTAFNTBPGGT1BFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793541-B1 | NCO-TERMINATED VINYL TELOMERS | NOVARTIS AG (CH) | 1999-09-22 | — | — | EP | disclosed |
| EP-0800657-B1 | POLYMERS BASED ON BLOCK COPOLYMERS | NOVARTIS AG (CH) | 1998-11-25 | — | — | EP | disclosed |
| EP-0455587-B1 | New polymers and hard gas-permeable contact lenses made therefrom | CIBA GEIGY AG (CH) | 1995-07-19 | — | — | EP | disclosed |
| EP-0538188-A1 | Propellane-containing copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0455587-A1 | New polymers and hard gas-permeable contact lenses made therefrom | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |