Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001231 | 1.00 | FNTA (0.35) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL8466015 | 0.91 | THRB (0.33) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL2474720 | 0.89 | TDP1 (0.35) | — | |
| SCHEMBL9743623 | 0.84 | THRB (0.34) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL10432248 | 0.84 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL886924 | 0.81 | FNTA (0.37) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL290897 | 0.81 | FNTA (0.37) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL3768509 | 0.80 | THRB (0.32) | FNTAFNTBTHRBPGGT1BALDH1A1 | |
| SCHEMBL3847687 | 0.79 | FNTA (0.36) | FNTAFNTBTHRBPGGT1BFFAR3 | |
| SCHEMBL5086044 | 0.79 | FNTA (0.36) | FNTAFNTBTHRBPGGT1BFFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3861039-B1 | HYDROGEL COMPOSITIONS | OPHTALMIC CIE (FR) | 2023-11-01 | — | — | EP | claimed |
| EP-2872105-B1 | IMPROVED COMPOSITIONS FOR ENDODONTIC PROCEDURES | DENTSPLY SIRONA INC (US) | 2021-03-31 | — | — | EP | claimed |
| EP-2625217-B1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2018-07-04 | — | — | EP | claimed |
| EP-2598937-B1 | AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF | NOVARTIS AG (CH) | 2016-06-29 | — | — | EP | claimed |
| US-9322960-B2 | Method of making a contact lens | COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) | 2016-04-26 | — | — | US | claimed |
| EP-2488895-B1 | METHOD OF MAKING A CONTACT LENS | SAUFLON CL LTD (GB) | 2015-11-25 | — | — | EP | claimed |
| EP-2432808-B1 | ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS | NOVARTIS AG (CH) | 2015-10-21 | — | — | EP | claimed |
| US-20150247956-A1 | METHOD OF MAKING A CONTACT LENS | COOPERVISION INTERNATIONAL LIMITED (GB) | 2015-09-03 | — | — | US | claimed |
| US-9057821-B2 | Method of making a contact lens | SAUFLON CL LIMITED (GB) | 2015-06-16 | — | — | US | claimed |
| EP-2307190-B1 | SILICONE-CONTAINING POLYMERIC MATERALS WITH HYDROLYZABLE GROUPS | NOVARTIS AG (CH) | 2015-03-18 | — | — | EP | claimed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | claimed |
| EP-0897399-B1 | ACRYLIC POLYMER COMPOUNDS | DU PONT (US) | 2002-01-02 | — | — | EP | claimed |
| EP-0692100-B1 | IMPROVED ITACONATE COPOLYMERIC COMPOSITIONS FOR CONTACT LENSES | POLYMER TECHNOLOGY CORP (US) | 1999-07-21 | — | — | EP | claimed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | claimed |
| EP-0401990-B1 | Prepolymers useful in biomedical devices | BAUSCH & LOMB (US) | 1995-08-02 | — | — | EP | claimed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |
| EP-0215817-B1 | CONTINUOUS-WEAR LENSES | Bausch & Lomb Incorporated (US) | 1991-03-13 | — | — | EP | claimed |
| US-4829137-A | Continuous-wear highly oxygen permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1989-05-09 | — | — | US | claimed |
| EP-0215817-A1 | CONTINUOUS-WEAR LENSES. | BAUSCH & LOMB (US) | 1987-04-01 | — | — | EP | claimed |
| WO-1986004341-A1 | CONTINUOUS-WEAR LENSES | BAUSCH AND LOMB INCORPORATED (US) | 1986-07-31 | — | — | WO | claimed |