Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.48 |
| ▸ | CA2 | P00918 | 13/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2867512 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2864157 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2861103 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2867768 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL21522353 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2865989 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2863234 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL3807368 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL2859554 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 | |
| SCHEMBL3809665 | 0.94 | CA1 (0.48) | CA1CA2CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964860-B1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | TOSOH CORP (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-20160368879-A1 | PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY | SAN-APRO LTD. (JP) | 2016-12-22 | — | — | US | disclosed |
| EP-3018182-A1 | PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY | San-Apro Limited (JP) | 2016-05-11 | — | — | EP | disclosed |
| EP-1348716-B1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL CO (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-7838611-B2 | Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer | TOSOH CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20090137755-A1 | ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER | TOSOH CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1964860-A1 | ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER | Tosoh Corporation (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7285616-B2 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-23 | — | — | US | disclosed |
| WO-2006066569-A2 | IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS | HÄRING, Thomas (DE) | 2006-06-29 | — | — | WO | disclosed |
| EP-1348716-A1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-10-01 | — | — | EP | disclosed |
| US-20030180596-A1 | Aromatic polymer, method for producing the same and uses thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-09-25 | — | — | US | disclosed |
| US-6599866-B2 | Fluorinated phosphate ester; wear resistance | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-29 | — | — | US | disclosed |
| US-20020179883-A1 | Servo valve erosion inhibited aircraft hydraulic fluids | EXXONMOBIL RESEARCH & ENGINEERING COMPANY | 2002-12-05 | — | — | US | disclosed |
| WO-2002086034-A1 | SERVO VALVE EROSION INHIBITED AIRCRAFT HYDRAULIC FLUIDS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368879-A1 | PHOTOACID GENERATOR, AND RESIN COMPOSITION FOR PHOTOLITHOGRAPHY | ARL1, GARS1, SPTBN1 | CA1 1104/4885CA2 893/4885CA12 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.