Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857073 | 0.85 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24746973 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24748578 | 0.80 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24746989 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24746660 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL25857060 | 0.73 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24746990 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL24746894 | 0.72 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL25857050 | 0.72 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAMEN1ALOX12 | |
| SCHEMBL24748588 | 0.71 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-07-20 | — | — | US | disclosed |
| US-11529315-B1 | Modified guanidine-containing polymers for biologic delivery | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | GMPS, RNMT, GUCY1A1 | ALDH1A1 1829/4885SMN1; SMN2 2647/4885NPC1 1081/4885 |
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | GMPS, RNMT, GUCY1A1 | ALDH1A1 1829/4885SMN1; SMN2 2647/4885NPC1 1081/4885 |
| US-11529315-B1 | Modified guanidine-containing polymers for biologic delivery | GMPS, RNMT, GUCY1A1 | ALDH1A1 1829/4885SMN1; SMN2 2647/4885NPC1 1081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.