SCHEMBL25857073

SCHEMBL25857073

C=CC1OC(C=C)C2C(=O)N(CCNC(=S)/N=C(\N)Nc3ccccc3)C(=O)C12

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.42
NPC1 O15118 5/20 0.33
RAB9A P51151 5/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
F13A1 P00488 1/20 0.32
TGM2 P21980 1/20 0.32
CYP1A2 P05177 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25857060 0.89 ALDH1A1 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857050 0.87 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL25857071 0.85 MEN1 (0.35) ALDH1A1MEN1KMT2AHTT
SCHEMBL25857062 0.85 ALDH1A1 (0.45) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL24748596 0.85 ALDH1A1 (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857078 0.83 ALDH1A1 (0.40) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857066 0.79 ALDH1A1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL24748578 0.78 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL25857056 0.77 ALDH1A1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1
SCHEMBL25857068 0.77 ALDH1A1 (0.46) ALDH1A1NPC1RAB9ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-10-31 US disclosed
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225982-A1 MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885NPC1 1081/4885RAB9A 1420/4885
US-11801228-B2 Modified guanidine-containing polymers for biologic delivery GMPS, RNMT, GUCY1A1 ALDH1A1 1829/4885NPC1 1081/4885RAB9A 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.