Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5132080 | 0.86 | CYP19A1 (0.49) | TDP1CETPMAPTKMT2AMEN1 | |
| SCHEMBL6592281 | 0.84 | MMP1 (0.42) | POLBCETPMAPTKMT2AMEN1 | |
| SCHEMBL6592271 | 0.84 | MMP1 (0.42) | POLBCETPMAPTKMT2AMEN1 | |
| SCHEMBL8964829 | 0.82 | TDP1 (0.62) | TDP1POLBMAPTKMT2AMEN1 | |
| SCHEMBL29151256 | 0.81 | MAPT (0.57) | TDP1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL29938120 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL24749554 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL3889845 | 0.77 | SLC6A4 (0.52) | TDP1POLBMAPTKMT2AMEN1 | |
| SCHEMBL24750221 | 0.77 | GAA (0.46) | CETPMAPTHTTGAA | |
| SCHEMBL31009437 | 0.76 | HSPB1 (0.50) | TDP1POLBMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2022219246-A1 | TEAD INHIBITORS | ORION CORPORATION (FI) | 2022-10-20 | — | — | WO | disclosed |