SCHEMBL2475431

SCHEMBL2475431

CCCCCCCCCC(C(=O)O)(C(C)CCCCC)C(C)CCCCC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.46
GPR84 Q9NQS5 7/20 0.46
FFAR1 O14842 2/20 0.46
MAPT P10636 1/20 0.44
LCK P06239 1/20 0.44
PPARD Q03181 1/20 0.44
ZDHHC20 Q5W0Z9 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
HSPD1 P10809 1/20 0.42
BLM P54132 1/20 0.42
HSPE1 P61604 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4920071 1.00 ACE2 (0.46) ACE2GPR84FFAR1MAPTLCK
SCHEMBL6667219 0.96 ACE2 (0.42) ACE2GPR84FFAR1MAPTLCK
SCHEMBL29100228 0.96 ACE2 (0.42) ACE2GPR84FFAR1MAPTLCK
Ethylene Glycol SCHEMBL8083787 0.95 ACE2 (0.42) ACE2GPR84FFAR1MAPTLCK
SCHEMBL517722 0.92 FFAR4 (0.56) GPR84FFAR1MAPTPPARDBLM
Glycerin SCHEMBL1091506 0.92 GPR84 (0.45) ACE2GPR84FFAR1MAPTFFAR4
SCHEMBL15281992 0.90 FFAR4 (0.53) GPR84FFAR1MAPTPPARDBLM
SCHEMBL3251856 0.87 THRA (0.38) ACE2GPR84FFAR1MAPTLCK
SCHEMBL16335066 0.84 HSPD1 (0.53) ACE2GPR84FFAR1MAPTLCK
SCHEMBL29167335 0.84 ACE2 (0.44) ACE2GPR84FFAR1MAPTLCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113226254-B Oil-in-water emulsion cosmetic containing retinol 株式会社资生堂 2024-02-23 CN claimed
EP-3006547-B1 FRAGRANCE-CONTAINING CAPSULE AND COSMETIC IN WHICH SAID CAPSULES ARE BLENDED SHISEIDO CO LTD (JP) 2019-10-30 EP claimed
EP-1466586-B1 Water-in-oil emulsion preparation for external use on skin NISSHIN OILLIO GROUP LTD (JP) 2011-10-12 EP claimed
WO-2024142911-A1 WATER-IN-OIL EMULSION COSMETIC 株式会社 資生堂 2024-07-04 WO disclosed
CN-118019518-A Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-05-10 CN disclosed
CN-115175662-B Cosmetic product 信越化学工业株式会社 2024-05-03 CN disclosed
CN-112996473-B Powder dispersion composition and dispersion method thereof 株式会社资生堂 2024-04-05 CN disclosed
CN-113693965-B External preparation for skin for improving wrinkles 宝丽化成工业有限公司 2024-03-29 CN disclosed
CN-114040746-B Oil-in-water type cleansing cosmetic 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-113710226-B Cosmetic material 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-113226254-B Oil-in-water emulsion cosmetic containing retinol 株式会社资生堂 2024-02-23 CN disclosed
US-20080031906-A1 Cosmetic Composition and Method for Producing the Same HAKUTO CO., LTD. (JP) 2008-02-07 US disclosed
EP-1330999-B1 MELANOGENESIS INHIBITORS AND WHITENING AGENTS COMPRISING ERGOSTEROL DERIVATIVE AND COMPOSITIONS CONTAINING ERGOSTEROL DERIVATIVE SAKAMOTO BIO CO LTD (JP) 2007-12-26 EP disclosed
EP-1820538-A1 COSMETICS AND PROCESS FOR PRODUCTION THEREOF Hakuto Co., Ltd (JP) 2007-08-22 EP disclosed
EP-1500385-A1 METHOD OF FOAM STABILIZATION FOR FOAM COSMETIC Hakuto Co., Ltd (JP) 2005-01-26 EP disclosed
EP-1486193-A1 METHOD OF STABILIZING SILICONE OIL-CONTAINING COSMETIC COMPOSITION Hakuto Co., Ltd (JP) 2004-12-15 EP disclosed
WO-2004062635-A1 COMPOSITIONS FOR SKIN LIGHTENING COMPRISING BIS-PANTOYL-CYSTAMINE DSM IP ASSETS B.V. (NL) 2004-07-29 WO disclosed
WO-2004062633-A1 HAIR CARE COMPOSITIONS COMPRISING BIS - PANTOYL - CYSTAMINE OR A DERIVATIVE THEREOF DSM IP ASSETS B.V. (NL) 2004-07-29 WO disclosed
US-20030190299-A1 Melanogenesis inhibitors and whitening agents comprising ergosterol derivative and compositions containing ergosterol derivative SAKAMOTO BIO CO., LTD. (JP) 2003-10-09 US disclosed
EP-1330999-A1 MELANOGENESIS INHIBITORS AND WHITENING AGENTS COMPRISING ERGOSTEROL DERIVATIVE AND COMPOSITIONS CONTAINING ERGOSTEROL DERIVATIVE Sakamoto Bio Co. Ltd. (JP) 2003-07-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080031906-A1 Cosmetic Composition and Method for Producing the Same LIPA, CUTA, PLIN3 ACE2 4879/4885GPR84 3473/4885FFAR1 2445/4885
US-20030190299-A1 Melanogenesis inhibitors and whitening agents comprising ergosterol derivative and compositions containing ergosterol derivative CYP51A1, TYR, CYP46A1 ACE2 2752/4885GPR84 1197/4885FFAR1 999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.