Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15716510 | 0.79 | ALDH1A1 (0.58) | PTGER1ALDH1A1CTSVCTSLLMNA | |
| SCHEMBL2473768 | 0.79 | LTB4R (0.50) | LTB4RLTB4R2ALDH1A1CTSVCTSL | |
| SCHEMBL18113230 | 0.77 | CA12 (0.65) | ALDH1A1CA12CA1CA2CA4 | |
| SCHEMBL21775799 | 0.77 | PTGER1 (0.49) | PTGER1LTB4RLTB4R2ALDH1A1CTSV | |
| SCHEMBL8980650 | 0.75 | MAOB (0.54) | PTGER1ALDH1A1CTSVCTSLLMNA | |
| SCHEMBL1396290 | 0.75 | ALDH1A1 (0.57) | PTGER1ALDH1A1CTSVCTSLHPGD | |
| SCHEMBL128058 | 0.74 | GLRA1 (0.57) | PTGER1ALDH1A1CTSVCTSLMRGPRX4 | |
| SCHEMBL10742332 | 0.74 | MRGPRX4 (0.43) | ALDH1A1MRGPRX4LMNAHPGDFOLH1 | |
| SCHEMBL3424839 | 0.74 | ALDH1A1 (0.55) | PTGER1ALDH1A1LMNAHPGDNR4A2 | |
| Hydrochloric Acid SCHEMBL18037169 | 0.74 | ALDH1A1 (0.55) | PTGER1ALDH1A1CTSVCTSLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370422-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | Fibrogen, Inc. (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010056767-A1 | THIOCHROMENE DERIVATIVES AS HIP HYDROXYLASE INHIBITORS | FIBROGEN, INC. (US) | 2010-05-20 | — | — | WO | disclosed |