Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24756639 | 0.85 | RAB9A (0.34) | ALDH1A1HPGDMCL1NPC1RAB9A | |
| SCHEMBL30136602 | 0.83 | RAB9A (0.40) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL24756665 | 0.83 | RAB9A (0.40) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL24756402 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL30136633 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL8081972 | 0.78 | MCL1 (0.48) | ALDH1A1HPGDMCL1NPC1RAB9A | |
| SCHEMBL24755682 | 0.74 | MCL1 (0.38) | ALDH1A1HPGDMCL1NPC1RAB9A | |
| SCHEMBL24756285 | 0.74 | RAB9A (0.54) | ALDH1A1SMN1; SMN2MCL1NPC1RAB9A | |
| SCHEMBL7458526 | 0.73 | ALDH1A1 (0.35) | ALDH1A1HPGDTSHRSMN1; SMN2MAPT | |
| SCHEMBL24756679 | 0.71 | RAB9A (0.54) | HPGDMCL1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334298-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | Scorpion Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022265993-A1 | UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |