Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742864 | 0.77 | NPY4R (0.38) | TLR2SIRT5ALB | |
| SCHEMBL25148125 | 0.73 | C3AR1 (0.35) | SIRT5SIRT6SIRT1ALB | |
| SCHEMBL16299579 | 0.73 | NOD1 (0.32) | SIRT5NOD1 | |
| SCHEMBL12157383 | 0.71 | SIRT6 (0.47) | TLR2SIRT5SIRT6SIRT1ALB | |
| SCHEMBL16283873 | 0.69 | NOD1 (0.47) | TLR2SIRT5SIRT6SIRT1ALB | |
| SCHEMBL24220334 | 0.69 | GRIA1 (0.42) | TLR2SIRT5SIRT6SIRT1ALB | |
| SCHEMBL24826060 | 0.69 | GRIA1 (0.40) | TLR2SIRT5SIRT6SIRT1ALB | |
| SCHEMBL20887854 | 0.69 | TLR2 (0.44) | TLR2SIRT5SIRT6SIRT1PTPN2 | |
| SCHEMBL22876028 | 0.68 | DPP7 (0.49) | DPP7NOD1GNAI3GNAO1GNAI1 | |
| SCHEMBL24308138 | 0.68 | SIRT6 (0.41) | TLR2SIRT5SIRT6SIRT1ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266068-A2 | GLP-1 RECEPTOR AGONISTS HAVING IMPROVED PHARMACOLOGICAL AND DRUG DELIVERY PROPERTIES | RESOLUTE BIO, INC. (US) | 2022-12-22 | — | — | WO | disclosed |