Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064609 | 0.87 | NOD1 (0.34) | NOD1SIRT5 | |
| SCHEMBL2742864 | 0.82 | NPY4R (0.38) | SIRT5 | |
| SCHEMBL8261480 | 0.79 | SIRT5 (0.44) | NOD1SIRT5 | |
| SCHEMBL14295763 | 0.78 | NOD1 (0.33) | NOD1SIRT5 | |
| SCHEMBL14951121 | 0.78 | NOD1 (0.32) | NOD1 | |
| SCHEMBL25148125 | 0.77 | C3AR1 (0.35) | SIRT5 | |
| SCHEMBL24756979 | 0.73 | TLR2 (0.40) | NOD1SIRT5 | |
| SCHEMBL14951733 | 0.73 | GNPAT (0.34) | NOD1F2 | |
| SCHEMBL468949 | 0.72 | KISS1R (0.36) | NOD1 | |
| SCHEMBL17521511 | 0.71 | SIRT5 (0.45) | NOD1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015936-A1 | SUBSTITUTED TETRAHYDRONAPHTHALENES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | SANOFI (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015936-A1 | SUBSTITUTED TETRAHYDRONAPHTHALENES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | PAH, MCHR1, DHPS | NOD1 3025/4885F2 3768/4885SIRT5 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.