Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 2/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17063707 | 0.98 | ALDH1A1 (0.48) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL6557029 | 0.92 | ALDH1A1 (0.46) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL30881868 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL6554889 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL19284562 | 0.87 | HTR6 (0.54) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL30735695 | 0.87 | HTR6 (0.54) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL19284717 | 0.85 | HTR2C (0.53) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL8117529 | 0.84 | DRD2 (0.47) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL25821914 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HPGDTDP1CYP3A4TSHR | |
| SCHEMBL8117454 | 0.76 | NSD2 (0.47) | ALDH1A1HPGDTDP1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417825-B | Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof | 山东大学 | 2024-06-28 | — | — | CN | claimed |
| CN-115322190-B | Pyridoimidazole acyl sulfonamide derivative, and preparation method and application thereof | 山东大学 | 2023-09-22 | — | — | CN | claimed |
| WO-2023143034-A1 | PYRIDOIMIDAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2023-08-03 | — | — | WO | claimed |
| CN-115417825-A | Five-membered or six-membered fused ring pyrimidine cyclopropyl naphthalene derivative and preparation method and application thereof | 山东大学 | 2022-12-02 | — | — | CN | claimed |
| CN-115322190-A | Pyridoimidazole acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2022-11-11 | — | — | CN | claimed |
| CN-113336769-B | Thienopyrimidine ketone acyl sulfonamide derivative as well as preparation method and application thereof | 山东大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114478522-A | Pyridoimidazole derivative and preparation method and application thereof | 山东大学 | 2022-05-13 | — | — | CN | claimed |
| EP-3495362-B1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | UNIV SHANDONG (CN) | 2021-10-27 | — | — | EP | claimed |
| CN-113336769-A | Thienopyrimidone acylsulfonamide derivative and preparation method and application thereof | 山东大学 | 2021-09-03 | — | — | CN | claimed |
| CN-111763218-B | Thienopyrimidinone thioglycolic acid derivative and preparation method and application thereof | 山东大学 | 2021-05-28 | — | — | CN | claimed |
| CN-111763218-A | Thienopyrimidinone thioglycolic acid derivative and preparation method and application thereof | 山东大学 | 2020-10-13 | — | — | CN | claimed |
| CN-110878045-A | Compound and preparation method and application thereof | 江西同和药业股份有限公司 | 2020-03-13 | — | — | CN | claimed |
| US-10399978-B2 | Imidazopyridine thioglycolic acid derivatives as potent inhibitors of human urate transporter 1 | SHANDONG UNIVERSITY (CN) | 2019-09-03 | — | — | US | claimed |
| US-20190225606-A1 | Novel Imidazopyridine Thioglycolic Acid Derivatives as Potent Inhibitors of Human Urate Transporter 1 | SHANDONG UNIVERSITY (CN) | 2019-07-25 | — | — | US | claimed |
| EP-3495362-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shandong University (CN) | 2019-06-12 | — | — | EP | claimed |
| US-20260062412-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-4647424-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-11-12 | — | — | EP | disclosed |
| WO-2007050087-A1 | N[S(4-aryl-triazol-3-yl)α -mercaptoacetyl]-p-amino benozoic acids AS HIV REVERSE TRANSCRIPTASE INHIBITORS | ARDEA BIOSCIENCES, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060270725-A1 | N[S(4-aryl-triazol-3-yl)alpha-mercaptoacetyl]-p-amino benzoic acids as HIV reverse transcriptase inhibitors | ARDEA BIOSCIENCES, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2006026356-A2 | S-TRIAZOLYL α-MERCAPTOACETANILDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE | ARDEA BIOSCIENCES, INC. (US) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225606-A1 | Novel Imidazopyridine Thioglycolic Acid Derivatives as Potent Inhibitors of Human Urate Transporter 1 | SLC29A1, SLC28A1, SLC5A1 | ALDH1A1 446/4885HPGD 1753/4885TDP1 452/4885 |
| US-20060270725-A1 | N[S(4-aryl-triazol-3-yl)alpha-mercaptoacetyl]-p-amino benzoic acids as HIV reverse transcriptase inhibitors | NQO2, NAT1, QPCT | ALDH1A1 903/4885HPGD 1586/4885TDP1 3283/4885 |
| US-20260062412-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY | MYT1, NTMT1, MYL6 | ALDH1A1 2880/4885HPGD 2650/4885TDP1 1883/4885 |
| US-10399978-B2 | Imidazopyridine thioglycolic acid derivatives as potent inhibitors of human urate transporter 1 | SLC29A1, SLC28A1, SLC5A1 | ALDH1A1 473/4885HPGD 1343/4885TDP1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.