Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24761962 | 0.90 | CACNA1B (0.43) | ALDH1A1NPSR1ALOX15TP53MAPK1 | |
| SCHEMBL27238549 | 0.90 | CACNA1B (0.43) | ALDH1A1NPSR1ALOX15TP53MAPK1 | |
| SCHEMBL29764425 | 0.90 | CACNA1B (0.43) | ALDH1A1NPSR1ALOX15TP53MAPK1 | |
| SCHEMBL27238545 | 0.82 | CA12 (0.41) | ALDH1A1NPSR1CACNA1BCACNA1CHTR2A | |
| SCHEMBL24762020 | 0.76 | ALDH1A1 (0.35) | ALDH1A1NPSR1KMT2ACYP3A4CYP2C19 | |
| SCHEMBL24762224 | 0.76 | PDK2 (0.43) | ALDH1A1MAPK1KMT2ARORCPDK2 | |
| SCHEMBL24762022 | 0.73 | GPR119 (0.48) | ALDH1A1NPSR1ALOX15TP53MAPK1 | |
| SCHEMBL4776446 | 0.71 | HPGD (0.48) | ALDH1A1NPSR1L3MBTL1MEN1KMT2A | |
| SCHEMBL13209476 | 0.70 | CACNA1B (0.45) | ALDH1A1NPSR1ALOX15TP53MAPK1 | |
| SCHEMBL4123186 | 0.70 | CCR5 (0.47) | ALDH1A1MAPK1LMNAHTTHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |