Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762622 | 0.90 | RORC (0.38) | PDK2RORCKDM1A | |
| SCHEMBL24762625 | 0.88 | RORC (0.37) | PDK2RORCKDM1AALDH1A1TSHR | |
| SCHEMBL24761960 | 0.76 | ALDH1A1 (0.48) | PDK2RORCKDM1AUSP2ALDH1A1 | |
| SCHEMBL24762624 | 0.75 | CA1 (0.32) | ALDH1A1TSHRMAPK1KMT2A | |
| SCHEMBL24762620 | 0.73 | MMP13 (0.42) | RORCKMT2A | |
| SCHEMBL24762662 | 0.72 | LMNA (0.38) | ALDH1A1TSHR | |
| SCHEMBL24762658 | 0.70 | HDAC1 (0.36) | ALDH1A1TSHRKMT2A | |
| SCHEMBL20705482 | 0.69 | RAB9A (0.50) | PDK2KDM1AALDH1A1TSHR | |
| SCHEMBL4776446 | 0.67 | HPGD (0.48) | ALDH1A1TSHRKMT2A | |
| SCHEMBL12407134 | 0.66 | MMP2 (0.46) | ALDH1A1HCRTR2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |