Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 4/20 | 0.49 |
| ▸ | FPR2 | P25090 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512058 | 0.82 | LMNA (0.48) | TDP1FPR3FPR2USP2LMNA | |
| SCHEMBL24762604 | 0.81 | NPSR1 (0.58) | TDP1GAACYP3A4NPSR1 | |
| SCHEMBL23139878 | 0.81 | TDP1 (0.47) | TDP1MAOAMAOBCA12CA1 | |
| SCHEMBL25028474 | 0.79 | CA12 (0.70) | TDP1FPR3FPR2MGLLMAOA | |
| SCHEMBL21482939 | 0.79 | TDP1 (0.53) | TDP1FPR3FPR2USP2LMNA | |
| SCHEMBL18295921 | 0.79 | L3MBTL1 (0.55) | FPR3FPR2USP2LMNAMEN1 | |
| SCHEMBL2147505 | 0.77 | CA12 (0.69) | TDP1FPR3FPR2MGLLCA12 | |
| SCHEMBL23142808 | 0.77 | ALDH1A1 (0.46) | TDP1LMNAMGLLMAOAMAOB | |
| SCHEMBL2551512 | 0.77 | CA1 (0.53) | TDP1FPR3FPR2USP2LMNA | |
| SCHEMBL24762017 | 0.76 | ALDH1A1 (0.60) | TDP1FPR3FPR2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |