Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27238543 | 0.83 | HTT (0.47) | KDM1A | |
| SCHEMBL24762619 | 0.79 | HTR2A (0.45) | KDM1ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24762715 | 0.76 | CA12 (0.37) | KDM1ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24761961 | 0.75 | ALDH1A1 (0.38) | KDM1ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24762182 | 0.74 | PKM (0.55) | LMNAALDH1A1NPC1KMT2A | |
| SCHEMBL24762050 | 0.73 | LMNA (0.41) | LMNAALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL27238639 | 0.72 | ALDH1A1 (0.36) | KDM1ALMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL27238545 | 0.72 | CA12 (0.41) | ALDH1A1 | |
| SCHEMBL29799563 | 0.72 | PPARG (0.41) | LMNAALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL8444737 | 0.71 | SMN1; SMN2 (0.48) | KDM1AALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |