Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2471460 | 0.85 | EPHX2 (0.52) | EPHX2USP2P2RX7MEN1KMT2A | |
| SCHEMBL16564475 | 0.85 | P2RX7 (0.36) | CYP2C9P2RX7PIK3CANAMPTNMT1 | |
| SCHEMBL2478169 | 0.81 | ADRB1 (0.45) | TSHRTDP1 | |
| SCHEMBL2480175 | 0.81 | PKM (0.53) | EPHX2CYP2C9CYP2J2CYP2C19GRIN2B | |
| SCHEMBL2474778 | 0.79 | CTDSP1 (0.53) | USP2TSHRMEN1KMT2ACTDSP1 | |
| SCHEMBL2480695 | 0.79 | USP2 (0.45) | USP2TSHRMEN1KMT2ACTDSP1 | |
| SCHEMBL2471889 | 0.79 | MEN1 (0.58) | EPHX2USP2MEN1KMT2ACTDSP1 | |
| SCHEMBL2473352 | 0.79 | NPSR1 (0.58) | GRIN2BUSP2TSHRMEN1KMT2A | |
| SCHEMBL2480143 | 0.77 | EPHX2 (0.43) | EPHX2NAMPT | |
| SCHEMBL2474397 | 0.76 | KMT2A (0.51) | EPHX2CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | claimed |
| EP-2373620-A1 | NOVEL 4-(AZACYCLOALKYL)BENZENE-1,3-DIOL COMPOUNDS AS TYROSINASE INHIBITORS, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-10-12 | — | — | EP | disclosed |