Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24764604 | 0.88 | GPR119 (0.42) | GPR119 | |
| SCHEMBL31729058 | 0.83 | CYP3A4 (0.43) | GPR119 | |
| SCHEMBL34471700 | 0.83 | GPR119 (0.42) | GPR119DPP4 | |
| SCHEMBL31022118 | 0.83 | GPR119 (0.42) | GPR119DPP4 | |
| SCHEMBL31022332 | 0.83 | GPR119 (0.42) | GPR119DPP4 | |
| SCHEMBL30729623 | 0.82 | CXCR3 (0.50) | GPR119 | |
| SCHEMBL26958997 | 0.82 | CXCR3 (0.50) | GPR119 | |
| SCHEMBL31491286 | 0.82 | CXCR3 (0.50) | GPR119 | |
| SCHEMBL14465886 | 0.82 | CXCR3 (0.50) | GPR119 | |
| SCHEMBL20135390 | 0.81 | GPR119 (0.45) | GPR119SMARCA2SMARCA4PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184103-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉誉祥医药科技有限公司 | 2022-09-09 | — | — | WO | disclosed |