Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24766295 | 0.84 | MAPT (0.58) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL22062255 | 0.83 | SMN1; SMN2 (0.46) | MAPTHTTALDH1A1GAAMEN1 | |
| SCHEMBL24766019 | 0.82 | HSD11B1 (0.49) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL3734867 | 0.81 | MAPT (0.50) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL29191709 | 0.81 | MEN1 (0.62) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3734866 | 0.80 | MAPT (0.49) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL19308432 | 0.80 | MAPT (0.57) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL15869843 | 0.80 | MEN1 (0.54) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL30104122 | 0.79 | ALDH1A1 (0.49) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL15869835 | 0.78 | ALDH1A1 (0.48) | MAPTHTTNPSR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518768-B2 | Artificial metalloenzymes containing noble metal-porphyrins | PPIH, HMBS, PPOX | MAPT 3431/4885HTT 2491/4885NPSR1 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.