Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14595237 | 0.88 | TSHR (0.59) | MAPK1TSHRKDM4ELMNASMN1; SMN2 | |
| SCHEMBL5661304 | 0.85 | WDR5 (0.46) | WDR5MAPK1KDM4EKMT2AKCNH2 | |
| SCHEMBL5658758 | 0.85 | WDR5 (0.46) | WDR5MAPK1KDM4EKMT2AKCNH2 | |
| SCHEMBL15958920 | 0.83 | ADRB2 (0.59) | MAPK1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL9967717 | 0.82 | WDR5 (0.50) | WDR5MAPK1KDM4EKMT2AKCNH2 | |
| SCHEMBL28595280 | 0.81 | MAPK1 (0.66) | WDR5MAPK1TSHRKDM4EKMT2A | |
| SCHEMBL11446628 | 0.80 | WDR5 (0.49) | WDR5MAPK1TSHRKDM4EKMT2A | |
| SCHEMBL18969804 | 0.78 | LMNA (0.64) | MAPK1CYP2D6LMNA | |
| SCHEMBL96351 | 0.78 | LMNA (0.64) | MAPK1CYP2D6LMNA | |
| SCHEMBL31032827 | 0.78 | LMNA (0.64) | MAPK1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262350-A1 | SUBSTITUTED DIARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东第一医科大学(山东省医学科学院) | 2022-12-22 | — | — | WO | disclosed |