Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 9/20 | 0.54 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12302615 | 0.82 | WNT3A (0.63) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2183458 | 0.81 | WNT3A (0.47) | WNT3AAAK1CYP3A4PSEN1PSEN2 | |
| SCHEMBL15353584 | 0.81 | WNT3A (0.46) | WNT3ANSD2MTOR | |
| SCHEMBL24767209 | 0.81 | WNT3A (0.48) | WNT3AAAK1CYP3A4PSEN1PSEN2 | |
| SCHEMBL18703808 | 0.80 | WNT3A (0.47) | WNT3AAAK1CYP3A4MTORLRRK2 | |
| SCHEMBL22886742 | 0.78 | WNT3A (0.47) | WNT3AAAK1CYP3A4PSEN1PSEN2 | |
| SCHEMBL1912409 | 0.78 | PDE3B (0.45) | WNT3AAAK1NSD2MTOR | |
| SCHEMBL12302614 | 0.76 | WNT3A (0.55) | WNT3AAAK1CYP3A4PSEN1PSEN2 | |
| SCHEMBL24767287 | 0.76 | CCNC (0.37) | WNT3AMTOR | |
| SCHEMBL9377731 | 0.74 | CSNK2A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220281873-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2022-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220281873-A1 | COMPOUND AS PORCUPINE INHIBITOR AND USE THEREOF | PORCN, SLC6A1, SLC6A11 | WNT3A 1322/4885AAK1 2468/4885CYP3A4 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.