Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | CCNC | P24863 | 2/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434658 | 0.85 | CCNC (0.42) | ALDH1A1MAPTPOLBSIRT3TDP1 | |
| SCHEMBL8580162 | 0.81 | PKM (0.43) | SIRT3TDP1NAMPT | |
| SCHEMBL8746918 | 0.76 | NAPRT (0.47) | MAPTSIRT3TDP1GPR119KDM4C | |
| SCHEMBL26337351 | 0.75 | SIRT3 (0.50) | ALDH1A1MAPTPOLBSIRT3TDP1 | |
| SCHEMBL21241288 | 0.71 | SIRT3 (0.39) | ALDH1A1MAPTPOLBSIRT3TDP1 | |
| SCHEMBL13732150 | 0.70 | ALDH1A1 (0.46) | ALDH1A1MAPTSIRT3TDP1NAMPT | |
| SCHEMBL214076 | 0.69 | — | — | |
| SCHEMBL24492809 | 0.69 | TDP1 (0.35) | ALDH1A1MAPTPOLBSIRT3TDP1 | |
| SCHEMBL10061709 | 0.69 | ALDH1A1 (0.45) | ALDH1A1MAPTSIRT3TDP1NAMPT | |
| SCHEMBL10679852 | 0.69 | GPR119 (0.42) | ALDH1A1MAPTPOLBSIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872147-B1 | METHOD FOR MAKING CHIRAL OLIGONUCLEOTIDES | WAVE LIFE SCIENCES LTD (SG) | 2022-12-21 | — | — | EP | disclosed |