Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479940 | 0.92 | KDM4E (0.44) | KDM4ESMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2481800 | 0.83 | NPC1 (0.44) | KMT2AMEN1TSHR | |
| SCHEMBL12924998 | 0.83 | HRH3 (0.53) | KDM4EPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL991770 | 0.83 | PDK2 (0.48) | MMP2KDM4EPOLBALDH1A1DRD2 | |
| SCHEMBL2480421 | 0.82 | BCHE (0.41) | KMT2AMEN1TSHR | |
| SCHEMBL21595690 | 0.79 | DRD2 (0.60) | KDM4EPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2476605 | 0.79 | KDM4E (0.49) | MMP2KDM4EPOLBSMN1; SMN2KMT2A | |
| SCHEMBL12925007 | 0.78 | KCNH2 (0.43) | TSHRDRD2 | |
| SCHEMBL7994823 | 0.78 | LTA4H (0.56) | KDM4EPOLBSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21595642 | 0.78 | MMP2 (0.67) | MMP2KDM4EPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373694-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | BioMarin Pharmaceutical Inc. (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-2238102-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | Lead Therapeutics, Inc. (US) | 2010-10-13 | — | — | EP | disclosed |
| WO-2010065174-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009085562-A1 | NOVEL SEMI-SYNTHETIC GLYCOPEPTIDES AS ANTIBACTERIAL AGENTS | LEAD THERAPEUTICS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |