SCHEMBL24768690

SCHEMBL24768690

CC(C)(C)c1nc(-c2ccccc2)c2c(cc(-c3ccc(-c4nc(C(C)(C)C)nc5c4ccc4ccccc45)cc3)c3ccccc32)n1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.36
CNR2 P34972 3/20 0.35
CNR1 P21554 2/20 0.35
ALDH1A1 P00352 5/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 3/20 0.33
ACACA Q13085 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 1/20 0.32
PLA2G1B P04054 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
NUDT1 P36639 3/20 0.31
LTB4R Q15722 1/20 0.31
AKT1 P31749 1/20 0.30
AKT2 P31751 1/20 0.30
PRNP P04156 1/20 0.30
ADORA2A P29274 1/20 0.30
MEN1 O00255 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19162668 0.84 MAOA (0.38) MAOACNR2CNR1ALDH1A1MAPT
SCHEMBL19161960 0.84 MAOA (0.40) MAOACNR2CNR1ALDH1A1MAPT
SCHEMBL25878135 0.81 PPARG (0.41) CNR2CNR1ALDH1A1MAPTL3MBTL1
SCHEMBL25878131 0.80 ALDH1A1 (0.37) MAOACNR2CNR1ALDH1A1MAPT
SCHEMBL23473872 0.78 MAOA (0.39) MAOACNR2ALDH1A1MAPTKDM4E
SCHEMBL19161274 0.78 PTGES (0.41) ALDH1A1MAPTKDM4EHPGDL3MBTL1
SCHEMBL19162667 0.78 MAPT (0.40) MAOACNR2CNR1ALDH1A1MAPT
SCHEMBL19162434 0.78 MAPT (0.42) ALDH1A1MAPTKDM4EHPGDL3MBTL1
SCHEMBL21086068 0.76 ADORA2A (0.30) ALDH1A1MAPTKDM4EHPGDADORA2A
SCHEMBL22101162 0.74 ADORA3 (0.41) CNR2CNR1ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251077-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, SLCO2A1, SLCO2B1 MAOA 395/4885CNR2 3911/4885CNR1 3882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.