Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL727185 | 0.91 | CYP1A2 (0.62) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| SCHEMBL29995759 | 0.84 | CYP11B1 (0.65) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| SCHEMBL14257669 | 0.84 | CYP1A2 (0.56) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| SCHEMBL177863 | 0.84 | CYP11B1 (0.65) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| Ammonia Solution, Strong SCHEMBL5999508 | 0.82 | CYP11B1 (0.62) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| Hydrochloric Acid SCHEMBL10665044 | 0.82 | TBXAS1 (0.64) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| SCHEMBL609110 | 0.81 | CALM1 (0.60) | HRH3CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL12009180 | 0.80 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL25181727 | 0.79 | CYP11B1 (0.56) | CYP1A2CYP2D6HRH4HRH3CYP11B1 | |
| SCHEMBL18459207 | 0.79 | CYP11B1 (0.56) | CYP1A2CYP2D6HRH4HRH3CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | Smilebiotek Zhuhai Limited (CN) | 2024-06-25 | — | — | US | disclosed |
| WO-2022263800-A1 | PROCESS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2022-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12016312-B2 | Animal models, screening methods, and treatment methods for intraocular diseases or disorders | MB, MYOC, PDE6A | CYP1A2 4430/4885CYP2D6 4661/4885HRH4 2567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.