Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783530 | 0.86 | IKBKE (0.41) | IKBKETBK1NPC1ALDH1A1POLB | |
| SCHEMBL16070840 | 0.85 | HDAC1 (0.40) | TBK1ARALDH1A1TSHRHSD17B10 | |
| SCHEMBL25953850 | 0.84 | SLC6A3 (0.44) | ALDH1A1TSHRHSD17B10KDM4EHPGD | |
| SCHEMBL15778750 | 0.84 | SLC6A3 (0.44) | ALDH1A1TSHRHSD17B10KDM4EHPGD | |
| SCHEMBL25422162 | 0.83 | ALDH1A1 (0.42) | IKBKETBK1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL13544329 | 0.82 | ACMSD (0.45) | ALDH1A1TSHRSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3903392 | 0.80 | ACMSD (0.47) | ALDH1A1TSHRSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3496971 | 0.79 | RAB9A (0.49) | NPC1ALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL16070837 | 0.78 | PDE4A (0.44) | IKBKETBK1ARALDH1A1TSHR | |
| SCHEMBL31584022 | 0.78 | TLR9 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BEONE MEDICINES I GMBH (CH) | 2022-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402915-A1 | BCL-2 INHIBITORS | BCL2, BCL2L1, BCL2L2 | IKBKE 123/4885TBK1 2565/4885AR 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.