Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.57 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desmethylselegiline SCHEMBL4543249 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| Rnordeprenyl SCHEMBL12171086 | 1.00 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| Desmethylselegiline SCHEMBL27813529 | 0.98 | CYP1A2 (0.96) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| Rnordeprenyl SCHEMBL29015119 | 0.98 | CYP1A2 (0.96) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| Rnordeprenyl SCHEMBL2473190 | 0.98 | CYP1A2 (0.96) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| Desmethylselegiline SCHEMBL27813455 | 0.96 | CYP1A2 (0.93) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| SCHEMBL16335536 | 0.81 | CYP1A2 (0.68) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| SCHEMBL29059547 | 0.79 | SIGMAR1 (0.81) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| SCHEMBL18756829 | 0.79 | CYP1A2 (0.65) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 | |
| SCHEMBL7031931 | 0.78 | CYP1A2 (0.64) | CYP1A2CYP3A4CYP2D6TSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642721-B | Preparation method of selegiline hydrochloride | 安徽贝克生物制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110668951-B | Synthesis process of selegiline hydrochloride | 安徽贝克生物制药有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110668951-A | Synthesis process of selegiline hydrochloride | 安徽贝克生物制药有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-110642721-A | Preparation method of selegiline hydrochloride | 安徽贝克生物制药有限公司 | 2020-01-03 | — | — | CN | disclosed |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2019-04-23 | — | — | US | disclosed |
| US-20180022719-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PIRAMAL IMAGING SA (CH) | 2018-01-25 | — | — | US | disclosed |
| US-20180022719-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PIRAMAL IMAGING SA (CH) | 2018-01-25 | — | — | US | disclosed |
| EP-2388245-B1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | disclosed |
| EP-2388245-B1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-07-12 | — | — | EP | disclosed |
| US-9682944-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PIRAMAL IMAGING SA (CH) | 2017-06-20 | — | — | US | disclosed |
| US-20090191129-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | Lantheus Biosciences Ltd. (GB) | 2009-07-30 | — | — | US | disclosed |
| US-20090191129-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | Lantheus Biosciences Ltd. (GB) | 2009-07-30 | — | — | US | disclosed |
| EP-2053033-A1 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | Bayer Schering Pharma AG (DE) | 2009-04-29 | — | — | EP | disclosed |
| US-20090048229-A1 | Methods for promoting wakefulness | COLUCID PHARMACEUTICALS, INC. | 2009-02-19 | — | — | US | disclosed |
| US-20090048229-A1 | Methods for promoting wakefulness | COLUCID PHARMACEUTICALS, INC. | 2009-02-19 | — | — | US | disclosed |
| WO-2009011901-A2 | METHODS FOR PROMOTING WAKEFULNESS | COLUCID PHARMACEUTICALS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| US-20070275959-A1 | Carbamoyl Esters That Inhibit Cholinesterase And Release Pharmacologically Active Agents | SENTION, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20070275959-A1 | Carbamoyl Esters That Inhibit Cholinesterase And Release Pharmacologically Active Agents | SENTION, INC. | 2007-11-29 | — | — | US | disclosed |
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | disclosed |
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | JENRIN DISCOVERY (US) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022719-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PMP22, MEN1, VHL | CYP1A2 4196/4885CYP3A4 4602/4885CYP2D6 4401/4885 |
| US-10266506-B2 | Compounds for use in imaging, diagnosing and/or treatment of diseases of the central nervous system or of tumors | PMP22, MEN1, VHL | CYP1A2 4196/4885CYP3A4 4602/4885CYP2D6 4401/4885 |
| US-20070078172-A1 | MAO-B INHIBITORS USEFUL FOR TREATING OBESITY | MAOB, MAOA, GPR119 | CYP1A2 184/4885CYP3A4 805/4885CYP2D6 713/4885 |
| US-20070275959-A1 | Carbamoyl Esters That Inhibit Cholinesterase And Release Pharmacologically Active Agents | ACHE, BCHE, CHAT | CYP1A2 309/4885CYP3A4 232/4885CYP2D6 382/4885 |
| US-20090048229-A1 | Methods for promoting wakefulness | HCRTR2, HCRTR1, CHAT | CYP1A2 2828/4885CYP3A4 1913/4885CYP2D6 3030/4885 |
| US-20090191129-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PMP22, MEN1, VHL | CYP1A2 4196/4885CYP3A4 4602/4885CYP2D6 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.