Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.49 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354085 | 0.85 | ALDH1A1 (0.64) | MAPTGBA1KDM4EALDH1A1HPGD | |
| SCHEMBL18153314 | 0.83 | LMNA (0.66) | LMNAMAPTGBA1KDM4EALDH1A1 | |
| SCHEMBL18063521 | 0.76 | MAPT (0.58) | LMNAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL18087196 | 0.74 | LMNA (0.60) | LMNAMAPTGBA1KDM4EALDH1A1 | |
| SCHEMBL21015066 | 0.74 | LMNA (0.62) | LMNAMAPTGBA1KDM4EALDH1A1 | |
| SCHEMBL7176075 | 0.73 | SMN1; SMN2 (0.71) | LMNAKDM4EALDH1A1TSHRL3MBTL1 | |
| SCHEMBL18153366 | 0.73 | MAPT (0.51) | LMNAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL3796501 | 0.72 | MAPT (0.70) | LMNAMAPTALDH1A1HSD17B10NPSR1 | |
| SCHEMBL11506640 | 0.72 | GALR2 (0.66) | LMNAMAPTKDM4ENPSR1 | |
| SCHEMBL18063516 | 0.71 | LMNA (0.72) | LMNAMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261296-A1 | COMPOUNDS THAT BIND NON-CANONICAL G-QUADRUPLEX STRUCTURES AND METHODS OF MAKING AND USING THE SAME | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-12-15 | — | — | WO | disclosed |