Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.36 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.36 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.36 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30103072 | 1.00 | KDM1A (0.40) | KDM1ACYP1A1CYP1B1LRRK2CYP1A2 | |
| SCHEMBL24784608 | 0.85 | KDM1A (0.40) | KDM1ACYP1A1CYP1B1LRRK2CYP1A2 | |
| SCHEMBL30103025 | 0.77 | CLK4 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL24785078 | 0.77 | CLK4 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL25365883 | 0.76 | ABL1 (0.44) | KDM1ACYP1A1CYP1B1CYP1A2CYP2E1 | |
| SCHEMBL30103056 | 0.76 | CLK4 (0.56) | CLK4 | |
| SCHEMBL1662528 | 0.75 | CYP4F2 (0.41) | CYP4F2CYP4A11ALKBH1GRIN1GRIN2B | |
| SCHEMBL29359230 | 0.75 | CYP4F2 (0.41) | CYP4F2CYP4A11ALKBH1GRIN1GRIN2B | |
| SCHEMBL30103016 | 0.74 | CYP1A2 (0.52) | KDM1ACYP1A1CYP1B1LRRK2CYP1A2 | |
| SCHEMBL24785077 | 0.72 | KDM1A (0.42) | KDM1AGRK6ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |