SCHEMBL24784635 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	ALKBH1	Q13686	1/20	0.36

▸	GRIN1	Q05586	7/20	0.35

▸	GRIN2B	Q13224	7/20	0.35

▸	PTPN1	P18031	2/20	0.34

▸	FPR1	P21462	1/20	0.33

▸	FPR2	P25090	1/20	0.33

▸	DHODH	Q02127	1/20	0.33

▸	ROCK2	O75116	1/20	0.33

▸	GRK6	P43250	1/20	0.33

▸	LDHA	P00338	1/20	0.33

▸	RORC	P51449	1/20	0.33

▸	CPT1A	P50416	1/20	0.32

▸	CPT1B	Q92523	1/20	0.32

▸	EGLN1	Q9GZT9	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30103142	1.00	ALKBH1 (0.36)	ALKBH1GRIN1GRIN2BPTPN1FPR1
SCHEMBL24784634	0.92	GRIN1 (0.34)	ALKBH1GRIN1GRIN2BFPR1FPR2
SCHEMBL30017932	0.92	GRIN1 (0.34)	ALKBH1GRIN1GRIN2BFPR1FPR2
SCHEMBL30103033	0.91	ALKBH1 (0.41)	ALKBH1GRIN1GRIN2BPTPN1DHODH
SCHEMBL24785460	0.91	ALKBH1 (0.41)	ALKBH1GRIN1GRIN2BPTPN1DHODH
SCHEMBL24784619	0.87	P2RX7 (0.38)	ALKBH1GRIN1GRIN2BPTPN1DHODH
SCHEMBL30103035	0.87	P2RX7 (0.38)	ALKBH1GRIN1GRIN2BPTPN1DHODH
SCHEMBL24785112	0.85	LDHA (0.36)	ALKBH1GRIN1GRIN2BPTPN1FPR1
SCHEMBL30018051	0.85	LDHA (0.36)	ALKBH1GRIN1GRIN2BPTPN1FPR1
SCHEMBL24784631	0.84	CNR2 (0.35)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022257960-A1	BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES	武汉人福创新药物研发中心有限公司	2022-12-15	—	—	WO	disclosed