Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.37 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.37 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.37 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.37 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30018769 | 1.00 | GRM5 (0.44) | GRM5KDM1ALRRK2PGRCYP1A1 | |
| SCHEMBL24784608 | 0.78 | KDM1A (0.40) | KDM1ALRRK2PGRCYP1A1CYP1A2 | |
| SCHEMBL4695771 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL24785094 | 0.74 | CLK4 (0.63) | CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL24784552 | 0.72 | CLK4 (0.56) | — | |
| SCHEMBL202404 | 0.71 | ALDH1A1 (0.61) | GRM5KDM1APGRCYP1A1CYP1A2 | |
| SCHEMBL31128598 | 0.70 | NOTUM (0.46) | GRM5KDM1ALRRK2 | |
| SCHEMBL509576 | 0.69 | ALDH1A1 (0.58) | GRM5KDM1APGRCYP1A1CYP1A2 | |
| SCHEMBL16951966 | 0.68 | PDE4A (0.38) | — | |
| SCHEMBL20282676 | 0.68 | ALDH1A1 (0.46) | GRM5KDM1ALRRK2PGRCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257960-A1 | BICYCLIC COMPOUND FOR THE TREATMENT OF EP2 AND EP4 RECEPTOR-MEDIATED DISEASES | 武汉人福创新药物研发中心有限公司 | 2022-12-15 | — | — | WO | disclosed |