SCHEMBL247883

SCHEMBL247883

Cc1ccc(C(=O)c2cccc(P)c2C(=O)c2ccc(C)c(C)c2C)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.35
CYP2C9 P11712 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 3/20 0.33
MEN1 O00255 1/20 0.33
AKR1B10 O60218 1/20 0.33
TRPA1 O75762 1/20 0.33
ABCB11 O95342 1/20 0.33
DHFR P00374 1/20 0.33
MPO P05164 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM1 P11229 1/20 0.33
AKR1B1 P15121 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
HIF1A Q16665 1/20 0.33
NAPRT Q6XQN6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4583582 0.86 CYP3A4 (0.39) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL9309416 0.81 ESR1 (0.46) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL8732527 0.78 TDP2 (0.36) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL17085772 0.78 LMNA (0.35) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL7183110 0.77 ALDH1A1 (0.36) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL28036413 0.75 MAPK13 (0.46) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL247465 0.75 KMT2A (0.43) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL7183628 0.73 CYP3A4 (0.42) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL29515031 0.72 KMT2A (0.52) CYP3A4CYP2C9KMT2ALMNAMEN1
SCHEMBL310386 0.72 KMT2A (0.52) CYP3A4CYP2C9KMT2ALMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016166470-A1 METHOD FOR DUAL PHOTOCHEMICAL/THERMAL CROSSLINKING ACTIVATABLE UNDER UV/VISIBLE IRRADIATION, AND COMPOSITION FOR IMPLEMENTING SAID METHOD UNIVERSITÉ DE HAUTE-ALSACE (FR) 2016-10-20 WO claimed
WO-2020064849-A1 PHOTO-CROSSLINKABLE COMPOSITIONS FOR FABRICS CLIPSO PRODUCTIONS (FR) 2020-04-02 WO disclosed
EP-3526297-A1 THERMOFORMABLE AND SCRATCH-RESISTANT PHOTOPOLYMER COATINGS Université de Haute Alsace (FR) 2019-08-21 EP disclosed
WO-2018069644-A1 THERMOFORMABLE AND SCRATCH-RESISTANT PHOTOPOLYMER COATINGS UNIVERSITÉ DE HAUTE-ALSACE (FR) 2018-04-19 WO disclosed
WO-2016166470-A1 METHOD FOR DUAL PHOTOCHEMICAL/THERMAL CROSSLINKING ACTIVATABLE UNDER UV/VISIBLE IRRADIATION, AND COMPOSITION FOR IMPLEMENTING SAID METHOD UNIVERSITÉ DE HAUTE-ALSACE (FR) 2016-10-20 WO disclosed
EP-2588549-A1 D1479 STABLE LIQUID BAP PHOTOINITIATOR AND ITS USE IN RADIATION CURABLE COMPOSITIONS DSM IP Assets B.V. (NL) 2013-05-08 EP disclosed
WO-2012003106-A1 D1479 STABLE LIQUID BAP PHOTOINITIATOR AND ITS USE IN RADIATION CURABLE COMPOSITIONS DSM IP ASSETS B.V. (NL) 2012-01-05 WO disclosed