SCHEMBL4583582

SCHEMBL4583582

Cc1ccc(C(=O)c2ccccc2P)c(C)c1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.39
CYP2C9 P11712 3/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.37
TP53 P04637 2/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LMNA P02545 3/20 0.37
CYP1A2 P05177 2/20 0.37
CHRM1 P11229 2/20 0.37
AKR1C3 P42330 2/20 0.37
HIF1A Q16665 2/20 0.37
MEN1 O00255 1/20 0.37
AKR1B10 O60218 1/20 0.37
TRPA1 O75762 1/20 0.37
ABCB11 O95342 1/20 0.37
DHFR P00374 1/20 0.37
MPO P05164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247883 0.86 CYP3A4 (0.35) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL28036413 0.85 MAPK13 (0.46) CYP3A4CYP2C9KMT2AALDH1A1LMNA
SCHEMBL8732527 0.84 TDP2 (0.36) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL9309416 0.82 ESR1 (0.46) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL7183110 0.82 ALDH1A1 (0.36) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL28410141 0.80 AKR1C3 (0.55) CYP3A4CYP2C9KMT2AALDH1A1GAA
SCHEMBL110064 0.77 CYP3A4 (0.37) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL671398 0.77 MEN1 (0.49) KMT2AALDH1A1TSHRGAASMN1; SMN2
SCHEMBL1874803 0.77 CYP3A4 (0.36) CYP3A4CYP2C9KMT2AALDH1A1TSHR
SCHEMBL6688725 0.77 CYP3A4 (0.36) CYP3A4CYP2C9KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104910207-B The preparation method of bis(benzoylphenyl) phosphine oxide and benzoyl diphenyl phosphine oxide 天津墨森科技有限公司 2019-03-05 CN claimed
EP-2296046-B1 Curable toner compositions and processes XEROX CORP (US) 2017-06-28 EP claimed
EP-2249211-B1 Electrostatographic machine comprising curable toner compositions XEROX CORP (US) 2017-04-19 EP claimed
CN-104151358-B The preparation method of two (2,4, the 6-trimethylbenzoyl) phenyl phosphine oxides of a kind of light trigger ZHANGJIAGANG JIMUTE CHEMICAL TECHNOLOGY CO., LTD. (CN) 2016-05-11 CN claimed
CN-102942593-B Synthetic method of photoinitiator dual (2,4,6-trimethylbenzene formyl group) phenyl phosphine oxide UNIV SHANDONG SCIENCE & TECH 2015-05-27 CN claimed
CN-104151358-A Preparation method for photoinitiator bis(2,4,6-trimethylbenzoyl)phenylphosphine oxide ZHANGJIAGANG JIMUTE CHEMICAL TECHNOLOGY CO LTD 2014-11-19 CN claimed
EP-2249210-B1 Curable toner compositions and processes XEROX CORP (US) 2014-11-05 EP claimed
CN-102942593-A Synthetic method of photoinitiator dual (2,4,6-trimethylbenzene formyl group) phenyl phosphine oxide UNIV SHANDONG SCIENCE & TECH 2013-02-27 CN claimed
CN-102471633-A D1479 Stable liquid bisacylphosphine photoinitiators and their use in radiation curable compositions DSM IP ASSETS BV 2012-05-23 CN claimed
CN-101450992-B Polymer and preparation method thereof and conducting resin containing the same BYD CO LTD 2010-12-22 CN claimed
CN-101450992-A Polymer and preparation method thereof and conducting resin containing the same BYD CO LTD (CN) 2009-06-10 CN claimed
EP-1593521-B1 Ink -Jettable Overprint Composition XEROX CORP (US) 2008-09-10 EP claimed
US-20210317297-A1 METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR STRUCTO PTE LTD (SG) 2021-10-14 US disclosed
EP-3820398-A1 METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR Structo Pte. Ltd. (SG) 2021-05-19 EP disclosed
EP-3303006-B1 FLAT MULTI-COMPOSIT REINFORCEMENT MICHELIN & CIE (FR) 2020-04-01 EP disclosed
CN-104910207-B The preparation method of bis(benzoylphenyl) phosphine oxide and benzoyl diphenyl phosphine oxide 天津墨森科技有限公司 2019-03-05 CN disclosed
CN-1248267-A (Co) polymers by photopolymerization CIBA SC HOLDING AG (CH) 2000-03-22 CN disclosed
CN-1248266-A Molecular weight controll polymers by photopolymerization DU PONT (US) 2000-03-22 CN disclosed
CN-1219245-A COATED OPTICAL FIBERS HAVING STRIPPABLE PRIMARY COATINGS AND PROCESSES FOR MAKING AND USING SAME BORDEN INC (US) 1999-06-09 CN disclosed
CN-1153926-A Oximesulfonic acid esters and use thereof as latent sulfonic acids CIBA GEIGY AG (CH) 1997-07-09 CN disclosed