Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478871 | 1.00 | MGLL (0.40) | MGLLAKR1C3TDP1APEX1 | |
| SCHEMBL2480356 | 0.87 | MGLL (0.38) | MGLLTDP1 | |
| SCHEMBL2480359 | 0.87 | MGLL (0.38) | MGLLTDP1 | |
| SCHEMBL2672628 | 0.82 | MGLL (0.43) | MGLLTDP1 | |
| SCHEMBL2672634 | 0.82 | MGLL (0.43) | MGLLTDP1 | |
| SCHEMBL2672639 | 0.82 | MGLL (0.43) | MGLLTDP1 | |
| SCHEMBL2474133 | 0.81 | MGLL (0.39) | MGLLTDP1 | |
| SCHEMBL2672425 | 0.81 | PAM (0.39) | MGLLTDP1 | |
| SCHEMBL2672423 | 0.81 | PAM (0.39) | MGLLTDP1 | |
| SCHEMBL2474137 | 0.81 | MGLL (0.39) | MGLLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2374788-A1 | INDANYL COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |
| EP-2374794-A1 | CYCLIC AMINE COMPOUNDS | Daiichi Sankyo Company, Limited (JP) | 2011-10-12 | — | — | EP | disclosed |