SCHEMBL24794292

SCHEMBL24794292

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4cccc5oc6ccc(-c7ccc8c(c7)C7(c9ccccc9-c9ccccc97)c7ccccc7-8)cc6c45)n3)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 8/20 0.36
PLA2G2A P14555 4/20 0.36
PLA2G4A P47712 4/20 0.36
PLA2G10 O15496 1/20 0.36
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
PRKDC P78527 1/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24795767 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24795709 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24794624 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24795338 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24795478 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24794935 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24795777 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24794363 1.00 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL25872111 0.99 PDK2 (0.35) PDK2PLA2G2APLA2G4APLA2G10PIM1
SCHEMBL24794356 0.99 PDK2 (0.36) PDK2PLA2G2APLA2G4APLA2G10PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228523-A1 Metal complexes UDC IRELAND LTD (IE) 2024-07-11 US disclosed
US-20240228523-A1 Metal complexes UDC IRELAND LTD (IE) 2024-07-11 US disclosed
WO-2024033282-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-02-15 WO disclosed
US-20230331754-A1 MONONUCLEAR TRIPODAL HEXADENTATE IRIDIUM COMPLEXES FOR USE IN OLEDS UDC IRELAND LIMITED (IE) 2023-10-19 US disclosed
US-20230331754-A1 MONONUCLEAR TRIPODAL HEXADENTATE IRIDIUM COMPLEXES FOR USE IN OLEDS UDC IRELAND LIMITED (IE) 2023-10-19 US disclosed
US-20230295104-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
US-20230295104-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-21 US disclosed
EP-4055641-B1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-07-19 EP disclosed
WO-2023110742-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-06-22 WO disclosed
US-20220407013-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2022-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331754-A1 MONONUCLEAR TRIPODAL HEXADENTATE IRIDIUM COMPLEXES FOR USE IN OLEDS OCIAD1, OCIAD2, NUDT1 PDK2 3432/4885PLA2G2A 2493/4885PLA2G4A 1717/4885
US-20240228523-A1 Metal complexes MCU, IMMT, SOD1 PDK2 2377/4885PLA2G2A 4016/4885PLA2G4A 4418/4885
US-20230295104-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, L1CAM, EPCAM PDK2 970/4885PLA2G2A 3935/4885PLA2G4A 4499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.