Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456981 | 0.79 | GABRA1 (0.43) | ALDH1A1HPGDGABRA1GABRB2DPP4 | |
| Hydrochloric Acid SCHEMBL739371 | 0.78 | GABRA1 (0.41) | ALDH1A1HPGDGABRA1GABRB2DPP4 | |
| Hydrochloric Acid SCHEMBL1727636 | 0.76 | DPP4 (0.40) | ALDH1A1HPGDGABRA1GABRB2DPP4 | |
| SCHEMBL8990154 | 0.75 | GABRA1 (0.43) | HPGDGABRA1GABRB2DPP4FAAH | |
| SCHEMBL14221891 | 0.74 | GABRA1 (0.46) | ALDH1A1HPGDGABRA1GABRB2DPP4 | |
| SCHEMBL29523444 | 0.73 | DPP4 (0.41) | HPGDMAPTGABRA1GABRB2DPP4 | |
| SCHEMBL30265954 | 0.72 | FAAH (0.43) | ALDH1A1HPGDMAPTGABRA1GABRB2 | |
| SCHEMBL15826554 | 0.72 | FAAH (0.43) | ALDH1A1HPGDMAPTGABRA1GABRB2 | |
| SCHEMBL20408268 | 0.72 | HTR7 (0.43) | ALDH1A1MAPTDPP4FAAHNR1H2 | |
| SCHEMBL21494571 | 0.71 | POLB (0.50) | SMN1; SMN2MAPTDPP4LMNANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10081666-A | — | — | None | — | — | JP | disclosed |
| US-6515129-B1 | A pharmaceutical composition which comprises, a cyclic imide derivative represented by the general formula (I): present invention relates to an aminopeptidase N inhibitor or an angiogenesis inhibitor, modulates production of tumor necrosis | ISHIHARA SANGYO KAISHA LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-6429212-B1 | AMINOPEPTIDASE N INHIBITOR USED TO TREAT CANCER, TUMORS, AND RETINOPATHY; FEW SIDE EFFECTS; ANGIOGENESIS INHIBITOR | ISHIHARA SANGYO KAISHA LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| JP-H1081666-A | PHTHALIMIDE DERIVATIVE OR SALT THEREOF, ITS PRODUCTION AND MEDICINAL COMPOSITION CONTAINING THE SAME | ISHIHARA SANGYO KAISHA LTD | 1998-03-31 | — | — | JP | disclosed |