Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664406 | 0.81 | HIF1A (0.40) | HIF1ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL11208899 | 0.77 | HIF1A (0.41) | HIF1ASMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL4983840 | 0.75 | HIF1A (0.42) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL21658639 | 0.75 | GRM4 (0.47) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL21976909 | 0.72 | FAAH (0.43) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL20229553 | 0.72 | FAAH (0.43) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL24796251 | 0.71 | LMNA (0.44) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL7966160 | 0.71 | FAAH (0.42) | FAAHMGLLHIF1ASMN1; SMN2NPC1 | |
| SCHEMBL21976453 | 0.70 | FAAH (0.44) | FAAHMGLLSMN1; SMN2NPC1RAB9A | |
| SCHEMBL890241 | 0.70 | HIF1A (0.42) | HIF1ASMN1; SMN2NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535599-B2 | Benzisoxazole derivative | Sumitomo Pharma Co., Ltd. (JP) | 2022-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535599-B2 | Benzisoxazole derivative | HDAC3, GABRA5, HDAC2 | FAAH 1628/4885MGLL 4094/4885HIF1A 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.