Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NAMPT | P43490 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377084 | 0.93 | MAPT (0.43) | MAPTKMT2AHTTLMNAMEN1 | |
| SCHEMBL19377494 | 0.88 | MAPT (0.43) | MAPTKMT2AHTTLMNAMEN1 | |
| SCHEMBL19377587 | 0.80 | DRD2 (0.38) | MAPTKMT2AMEN1GAARAB9A | |
| SCHEMBL19377435 | 0.78 | HSD17B10 (0.46) | KMT2AMEN1ALDH1A1NAMPTPOLB | |
| SCHEMBL19377014 | 0.77 | MEN1 (0.39) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL19384137 | 0.74 | MLNR (0.39) | KMT2AMEN1RAB9A | |
| SCHEMBL19377308 | 0.74 | ROCK2 (0.43) | MAPTKMT2AHTTLMNAMEN1 | |
| SCHEMBL19377297 | 0.73 | GHSR (0.47) | MAPTKMT2AHTTLMNAMEN1 | |
| SCHEMBL24800035 | 0.73 | KMT2A (0.44) | MAPTKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL24800034 | 0.72 | GHSR (0.50) | MAPTKMT2AHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390355-B1 | BENZENESULFONYL-ASYMMETRIC UREAS AND MEDICAL USES THEREOF | HELSINN HEALTHCARE SA (CH) | 2022-12-28 | — | — | EP | disclosed |