Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256737 | 0.82 | DCLRE1B (0.40) | DCLRE1ADCLRE1BCYP1A2KDM4EMAPT | |
| SCHEMBL5374764 | 0.80 | APEX1 (0.57) | APEX1AKR1B1DCLRE1ADCLRE1BCYP1A2 | |
| SCHEMBL21464343 | 0.78 | CA2 (0.55) | APEX1AKR1B1MAPTALDH1A1MEN1 | |
| SCHEMBL30301887 | 0.77 | KDM4E (0.48) | APEX1AKR1B1KDM4EMEN1KMT2A | |
| SCHEMBL1022607 | 0.77 | SMN1; SMN2 (0.57) | APEX1DCLRE1BKDM4EMAPTALDH1A1 | |
| SCHEMBL2923481 | 0.77 | TSHR (0.50) | APEX1AKR1B1DCLRE1ADCLRE1BKDM4E | |
| SCHEMBL2042628 | 0.77 | KDM4E (0.48) | APEX1AKR1B1KDM4EMEN1KMT2A | |
| SCHEMBL2336414 | 0.77 | SRC (0.54) | APEX1KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL8235153 | 0.77 | AKR1B1 (0.39) | APEX1AKR1B1CYP1A2KDM4EMAPT | |
| SCHEMBL2386421 | 0.77 | KDM4E (0.55) | APEX1AKR1B1DCLRE1ADCLRE1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272036-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |