Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1B | Q9H816 | 3/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24801286 | 0.82 | APEX1 (0.44) | DCLRE1BDCLRE1ACYP1A2ALDH1A1TSHR | |
| SCHEMBL1408523 | 0.79 | KDM4E (0.50) | DCLRE1BDCLRE1ACYP1A2ALDH1A1TSHR | |
| SCHEMBL256719 | 0.78 | TDP1 (0.41) | DCLRE1BDCLRE1ACYP1A2ALDH1A1TSHR | |
| SCHEMBL13981636 | 0.78 | PTPN1 (0.53) | DCLRE1BDCLRE1ATSHRCA1CA2 | |
| SCHEMBL8479639 | 0.78 | CA12 (0.47) | DCLRE1BDCLRE1ACYP1A2ALDH1A1TSHR | |
| SCHEMBL11230553 | 0.78 | ALDH1A1 (0.57) | DCLRE1BDCLRE1ACYP1A2HMGB1CXCL12 | |
| SCHEMBL13652578 | 0.76 | ALDH1A1 (0.48) | CYP1A2ALDH1A1TSHRCA12CA1 | |
| SCHEMBL3746157 | 0.76 | PTGDR2 (0.53) | DCLRE1BDCLRE1AKDM4E | |
| SCHEMBL8768830 | 0.76 | KDM4E (0.57) | DCLRE1BDCLRE1ACYP1A2ALDH1A1CASP1 | |
| SCHEMBL365167 | 0.76 | KEAP1 (0.50) | DCLRE1BDCLRE1ACYP1A2HMGB1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012029942-A1 | CYCLIC AMIDE DERIVATIVE | 大日本住友製薬株式会社 (JP) | 2012-03-08 | — | — | WO | disclosed |