Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15390567 | 0.83 | APOBEC3G (0.44) | APOBEC3GCHRNEPDCD1CD274LMNA | |
| SCHEMBL720119 | 0.76 | CYP3A4 (0.43) | APOBEC3GCHRNEPDCD1CD274GABRA1 | |
| SCHEMBL14534162 | 0.76 | KDM4E (0.39) | APOBEC3GCHRNEPDCD1CD274LMNA | |
| SCHEMBL12319786 | 0.75 | — | — | |
| SCHEMBL11744835 | 0.74 | PNMT (0.43) | APOBEC3GCHRNEPDCD1CD274 | |
| SCHEMBL3167058 | 0.74 | G6PD (0.43) | APOBEC3GCHRNEPDCD1CD274HSPA5 | |
| SCHEMBL31033256 | 0.74 | G6PD (0.43) | APOBEC3GCHRNEPDCD1CD274HSPA5 | |
| SCHEMBL10278897 | 0.74 | — | — | |
| SCHEMBL17549431 | 0.73 | GABRA1 (0.50) | APOBEC3GCHRNEPDCD1CD274LMNA | |
| SCHEMBL2717078 | 0.73 | TAAR1 (0.41) | APOBEC3GCHRNEPDCD1CD274ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272036-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-12-29 | — | — | WO | disclosed |