Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAE1 | Q13564 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23529335 | 0.94 | XDH (0.39) | PTGER4XDHIDO1NR1H4GPR35 | |
| SCHEMBL23529388 | 0.91 | IDO1 (0.39) | PTGER4XDHIDO1NR1H4GPR35 | |
| SCHEMBL23529398 | 0.86 | PTGER4 (0.38) | PTGER4NR1H4AGTR1 | |
| SCHEMBL23529311 | 0.83 | AGTR1 (0.42) | AGTR1 | |
| SCHEMBL29948116 | 0.82 | GPR35 (0.35) | NR1H4GPR35 | |
| SCHEMBL23529396 | 0.82 | GPR35 (0.35) | NR1H4GPR35 | |
| SCHEMBL23552631 | 0.80 | PKN1 (0.34) | — | |
| SCHEMBL29948157 | 0.80 | PKN1 (0.34) | — | |
| SCHEMBL23552642 | 0.80 | IDO1 (0.41) | PTGER4IDO1 | |
| SCHEMBL29948209 | 0.80 | IDO1 (0.41) | PTGER4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266711-A1 | SUBSTITUTED AMIDOBENZIMIDAZOLE DIMERS AS STING MODULATORS | Aculeus Therapeutics Pty Ltd (AU) | 2022-12-29 | — | — | WO | disclosed |