Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30942665 | 0.77 | KDM4E (0.43) | P2RX7KDM4EL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL16321386 | 0.75 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL30987262 | 0.75 | KDM4E (0.41) | KDM4EL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL27171657 | 0.73 | MAPT (0.53) | P2RX7KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL30713095 | 0.73 | MAPT (0.53) | P2RX7KDM4EL3MBTL1HPGDALDH1A1 | |
| SCHEMBL4886359 | 0.70 | KDM4E (0.40) | KDM4EL3MBTL1HPGDALDH1A1MEN1 | |
| SCHEMBL15710183 | 0.69 | CYP1A2 (0.50) | KDM4EL3MBTL1ALDH1A1MEN1MAPT | |
| SCHEMBL2051437 | 0.68 | NR3C2 (0.41) | KDM4EL3MBTL1HPGDALDH1A1MAPT | |
| SCHEMBL24306108 | 0.67 | GRM5 (0.47) | GRM5L3MBTL1HPGDALDH1A1POLB | |
| SCHEMBL4882320 | 0.66 | OXTR (0.49) | KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270976-A1 | NOVEL PYRIDINE DERIVATIVE COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2022-12-29 | — | — | WO | disclosed |