Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.49 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4886359 | 0.79 | KDM4E (0.40) | OXTRAVPR1AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL4988967 | 0.76 | KDM4E (0.56) | KDM4ESMN1; SMN2POLB | |
| SCHEMBL12075249 | 0.75 | KDM4E (0.58) | OXTRAVPR1ARAB9AKDM4EHTT | |
| SCHEMBL4875367 | 0.75 | HTR3E (0.38) | OXTRAVPR1AKDM4EPOLB | |
| SCHEMBL30942665 | 0.74 | KDM4E (0.43) | KDM4E | |
| SCHEMBL8673827 | 0.72 | RAB9A (0.44) | OXTRAVPR1ARAB9AHTTSMN1; SMN2 | |
| SCHEMBL31023204 | 0.72 | POLB (0.57) | OXTRAVPR1ARAB9AKDM4EHTT | |
| SCHEMBL9697055 | 0.72 | RAB9A (0.44) | OXTRAVPR1ARAB9AKDM4EBCHE | |
| SCHEMBL544026 | 0.72 | POLB (0.57) | OXTRAVPR1ARAB9AKDM4EHTT | |
| SCHEMBL1905339 | 0.72 | KDM5A (0.50) | OXTRAVPR1ARAB9APDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134517-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |
| CN-117050624-A | High-pressure salt-expelling film forming agent and preparation method thereof | 陕西佰亿盟能源科技有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-9375008-B2 | Pyrazole compounds for controlling invertebrate pests | BASF SE (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140142111-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | BASF SE (DE) | 2014-05-22 | — | — | US | disclosed |
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | ICAGEN, INC. (US) | 2008-03-13 | — | — | US | disclosed |
| US-7223782-B2 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | ICAGEN, INC. (US) | 2005-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142111-A1 | Pyrazole Compounds for Controlling Invertebrate Pests | NOX3, F3, F2 | OXTR 2075/4885AVPR1A 1964/4885RAB9A 2590/4885 |
| US-20080064690-A1 | PYRAZOLE-AMIDES AND -SULFONAMIDES | SCN3A, TRPV3, HCN3 | OXTR 2563/4885AVPR1A 1644/4885RAB9A 3176/4885 |
| US-20050049237-A1 | Pyrazole-amides and -sulfonamides | SCN3A, TRPV3, HCN3 | OXTR 2563/4885AVPR1A 1644/4885RAB9A 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.