Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321386 | 1.00 | KDM4E (0.41) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL30942665 | 0.83 | KDM4E (0.43) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4886359 | 0.75 | KDM4E (0.40) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL24802479 | 0.75 | GRM5 (0.41) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL15710183 | 0.75 | CYP1A2 (0.50) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL27971656 | 0.75 | POLB (0.47) | KDM4EALDH1A1TRPA1CYP17A1CYP1A2 | |
| SCHEMBL27955916 | 0.74 | P2RX7 (0.42) | KDM4E | |
| SCHEMBL2893944 | 0.74 | TRPA1 (0.41) | TRPA1CYP17A1CYP1A2TRPV1HSD11B1 | |
| SCHEMBL535580 | 0.72 | TRPA1 (0.42) | KDM4EL3MBTL1MEN1ALDH1A1MAPT | |
| SCHEMBL4882320 | 0.71 | OXTR (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024134517-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024134515-A1 | NOVEL COMPOUND AS RON INHIBITOR | 주식회사 엘지화학 | 2024-06-27 | — | — | WO | disclosed |