Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848205 | 0.74 | RECQL (0.36) | ALDH1A1TSHRTAAR1MEN1KMT2A | |
| SCHEMBL4772254 | 0.73 | L3MBTL1 (0.40) | LMNATSHRKDM4ECYP3A4CYP2D6 | |
| SCHEMBL11620669 | 0.72 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL1453183 | 0.72 | TSHR (0.36) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31558464 | 0.71 | SMN1; SMN2 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7505763 | 0.71 | SMN1; SMN2 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3227093 | 0.71 | CYP1A2 (0.44) | ALDH1A1KDM4ECYP3A4CYP2C19HSD17B10 | |
| SCHEMBL11202895 | 0.71 | TSHR (0.39) | LMNAALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL11624988 | 0.70 | LIPG (0.37) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL125255 | 0.70 | ALDH1A1 (0.57) | SLC6A4SLC6A2SLC6A3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024093-B2 | Fluorination of organic compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-05-05 | — | — | US | disclosed |
| US-20110312903-A1 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2011-12-22 | — | — | US | disclosed |
| EP-2376408-A2 | FLUORINATION OF ORGANIC COMPOUNDS | President and Fellows of Harvard College (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010059943-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110312903-A1 | FLUORINATION OF ORGANIC COMPOUNDS | SLCO1B3, SLCO2B1, FLI1 | SLC6A4 1349/4885SLC6A2 2290/4885SLC6A3 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.